Topic
Endocrine Disruptors
Endocrine Disruptors is a recurring research topic on Health Canon. This hub collects related explainers and protocols, newest first, each with evidence grades and practical decision frameworks.
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Environmental Health
Microplastic Polymer Types, Additives, and Leachables Explained
PET, PE, PVC, PS, and PP show up in blood, water, plaque, and organs—but additives like phthalates are a separate toxicology story from solid particles.
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Hormones & Genes
Synthetic Musks: Galaxolide, Tonalide, and Persistent Scent Bases
HHCB and AHTN replaced natural musk. They bioaccumulate in fat and breast milk—and face rising EU reproductive-toxicity scrutiny.
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Hormones & Genes
Estrogen Equivalents & Relative Potency: Turning Mixtures into E2-eq
E2-equivalent math multiplies concentration by relative potency—powerful for fish risk, dangerous when misapplied to human pills.
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Hormones & Genes
Parabens and Fragrance Mixtures: Preservatives Meet Scent Chemistry
Parabens preserve products; fragrance hides dozens of chemicals. Mixture exposure—not single-molecule purity theater—is the real dose story.
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Hormones & Genes
Fragrance Phthalates: DEP, MEP, and What Perfume Really Adds
DEP is the fragrance solvent most people actually carry. MEP tracks perfume use within hours—not DEHP plasticizer myths.
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Hormones & Genes
Fragrance Chemicals and Hormone Receptors: Mechanisms Without Myth
In vitro ER/AR signals, anti-androgenic phthalates, and musk receptor findings—graded carefully against human dose.
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Women's Health
Fragrance Chemicals, Female Reproduction, and Puberty Timing
Phthalates, parabens, and musks intersect female reproductive epidemiology—signals exist, certainty varies, vulnerable windows matter.
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Environmental Health
EE2 Chemistry & Related Estrogens: E1, E2, E3, Conjugates & Why Ethinyl Matters
17α-Ethinylestradiol is more potent and more persistent than natural estradiol—mass is not the same as estrogenic activity in water.
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Hormones & Genes
Fragrance Trade Secrets: Why “Fragrance” Hides Dozens of Chemicals
U.S. labels may legally collapse complex mixtures into one word. EU allergen rules and MoCRA are closing gaps—slowly—while most adults still misunderstand disclosure.
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Environmental Health
How Well Do Wastewater Plants Remove EE2 Birth-Control Estrogen?
Conventional plants partially remove ethinylestradiol—often ~50–80% depending on process—leaving ecological ng/L residues. Human drinking-water doses remain far below contraceptive pills.
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Environmental Health
PFAS Forever Chemicals: Complete Guide to Exposure, Health Evidence & Mitigation
EPA drinking-water MCLs are now 4.0 ppt for PFOA and PFOS. Here is how forever chemicals enter the body, what half-lives and biomonitoring tiers mean, and which filters actually work.
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Environmental Health
Endocrine-Disrupting Fragrances: Phthalates, Musks, Labels & Avoidance That Works
“Fragrance” on a U.S. label can hide dozens of chemicals. DEP tracks perfume use; DEHP is a stronger anti-androgen from plastics—and 35% of people report health effects from fragranced products.
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