Topic
Evidence
Evidence is a recurring research topic on Health Canon. This hub collects related explainers and protocols, newest first, each with evidence grades and practical decision frameworks.
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Nutrition
The Seed-Oil Evidence, Mapped (2026)
Map essential LA, RCT vs observational tension, frying oxidation, and pattern-first swaps—without purity cults.
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Environmental Health
Whole-House vs Point-of-Use Water Treatment: Choosing the Right Layer
POU RO/GAC targets drinking/cooking; whole-house systems address sediment, hardness, or volatile chemicals at every tap—with tradeoffs.
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Environmental Health
UV and Distillation for Drinking Water Pathogens: What They Do and Miss
UV inactivates many microbes without chemicals; distillation separates pure water vapor—neither is a universal metals/PFAS solution.
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Environmental Health
RO Remineralization Debate: Minerals, Taste, and What Evidence Actually Requires
RO strips dissolved solids; remineralization improves taste and can restore some hardness—diet remains the main mineral source for most people.
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Environmental Health
Heavy Metals in Drinking Water: Lead, Arsenic, and Copper Filter Priorities
Lead from plumbing, arsenic from geology, copper from corrosion—each needs different testing and treatment logic.
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Light & Recovery
Vitamin D Cutaneous Synthesis: UVB, Skin, Latitude, and What Windows Block
Skin makes vitamin D from UVB; glass, latitude, season, melanin, and age change yield—supplements fill gaps sunlight cannot.
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Fitness
Upper/Lower Split Programming for Men: Frequency, Volume, and Progression
Upper/lower splits hit muscles ~2×/week with manageable session length—strong default for intermediates chasing strength and hypertrophy.
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Light & Recovery
Sunlight and Skin Cancer Epidemiology: Risk Patterns Beyond Fear or Denial
UV is a major skin cancer driver; risk rises with cumulative and intense intermittent exposure, phenotype, and history.
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Light & Recovery
Sunlight Sex Axes: Vitamin D, Skin Cancer, and Shared Daylight Biology
Women show different vitamin D distributions and clothing/behavior patterns; men have distinct skin cancer mortality patterns in some datasets.
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Fitness
Strength Training Prescription for Women: Loading, Progression, and Underloading Traps
Women respond to progressive heavy loading; chronic underloading “for safety” is a common reason programs stall.
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Nutrition
Seed Oils in Special Populations: Pregnancy, Secondary Prevention, and Clinical Context
Essential FA needs, secondary-prevention trial limits, and frying exposure differ by clinical context—not by internet purity contests.
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Nutrition
Ramsden Reanalyses of Seed-Oil Era Trials: Sydney Diet Heart and Minnesota Coronary
Recovered data show pure high-linoleic interventions did not deliver the mortality free lunch mid-century narratives promised.
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Nutrition
Seed Oils on Sex Axes: Men, Women, Pregnancy, and What Trials Show
Men convert less ALA to EPA/DHA; pure-LA harm signals were male-heavy; pregnancy needs DHA—not zero linoleic acid.
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Nutrition
Seasonal and Regional Eating Decision Framework: Evidence vs Romanticism
Local and seasonal food can raise produce intake and cut some emissions—but is not automatically more nutritious or safer.
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Light & Recovery
Sauna Sex Axes: What Male KIHD Data Can and Cannot Say for Women
SCD and dementia HRs from Finnish men are not gender-swappable; pregnancy leads female risk.
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Light & Recovery
Red Light for Skin Photoaging: Dermatology Evidence Beyond Glow Masks
Multi-week red/NIR courses show collagen and wrinkle signals; selfie masks without dosimetry are not those trials.
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Light & Recovery
Red Light Therapy Sex Axes: Hair, Skin, Sports, and Pregnancy Firewalls
Men lead with AGA RCTs; women lead with FPHL and photoaging plus pregnancy pauses; testicle-light claims stay Grade D.
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Light & Recovery
Red Light for Hair vs Blood Sugar: Grade A LLLT vs Early Metabolic Pilots
Home hair LLLT has sham-controlled meta support; systemic glucose PBM remains a healthy-volunteer pilot—not diabetes care.
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Light & Recovery
Red Light Therapy Evidence Gaps: Hype, Failed Dosimetry, and Research Quality
PBM is real photobiology with uneven clinical maturity; parameter opacity and indication inflation create myths.
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Women's Health
PFAS and Women’s Health: Pregnancy, Lactation, and Sex-Axis Priorities
Women’s PFAS priorities center pregnancy hypertension, fetal growth, milk transfer, and breastfeeding defaults—not cosmetics panic.
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