Topic
Metabolic Health
Metabolic Health is a recurring research topic on Health Canon. This hub collects related explainers and protocols, newest first, each with evidence grades and practical decision frameworks.
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Metabolic Health
Hemochromatosis Phlebotomy Protocol: Induction and Maintenance Targets
Weekly units until ferritin 50–100 µg/L, then personalized maintenance—first-line for HFE overload.
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Metabolic Health
Exercise for Insulin Resistance: Aerobic, Resistance, and Concurrent Training
Muscle is a glucose sink. Training beats gadget stacks for IR when volume is real.
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Metabolic Health
Diabetes Diagnostic Criteria: FPG, OGTT, and HbA1c Explained
ADA cut points define dysglycemia categories—not HOMA-IR and not one restaurant spike.
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Metabolic Health
The Metabolic Labs Worth Requesting (2026)
Decision-grade lab roundup: glycemic criteria, HOMA-IR context, ApoB, iron studies, hs-CRP, and foundational CMP/TSH—without wellness panel maximalism.
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Women's Health
PCOS and Insulin Resistance in Women: Lean Phenotypes, GDM, Menopause
PCOS ~5–18%; IR often ~60–80% (lean still ~20–25%); GDM legacy and menopause as second IR windows—lifestyle first.
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Metabolic Health
Omega-6 to Omega-3 Ratio and Inflammation: What Human Evidence Shows
The ratio is real chemistry. Treating it as a CRP thermometer is not.
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Men's Health
Men’s Visceral Fat and Insulin Resistance: Why Waist Beats the Scale
Android fat, portal FFA, and higher IR at given BMI vs premenopausal women—lifestyle stack first, not red-light testosterone myths.
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Metabolic Health
Linoleic Acid Metabolism and OXLAMs: Pathways, Biomarkers, Limits
From LA to AA—and from LA to oxidized metabolites. Separate mechanism from population harm.
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Metabolic Health
Sydney and Minnesota Diet-Heart Reanalyses: What Ramsden Recovered
Cholesterol fell. Hard outcomes did not cooperate. How to read two recovered RCTs without slogans.
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Metabolic Health
Seed Oils Evidence Guide: Linoleic Acid Without the Culture War
Essential omega-6 biology, contested CVD trials, biomarker data, and the real frying-oil problem.
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Metabolic Health
Seed Oil Frying Oxidation: Aldehydes, Polar Compounds, and Reuse
The chemistry of abused fryer oil is clearer than the culture war over cold salad oil.
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Metabolic Health
Paul Saladino LDL, ApoB, and LMHR Risk Framing
TG down and HDL up do not cancel extreme ApoB. Measure; do not reassure by vibe.
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Metabolic Health
Iron Overload and Hemochromatosis: Labs, Genes, and Treatment
TSAT gates, ferritin myths, C282Y penetrance, phlebotomy targets, and why diet cannot replace blood removal.
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Metabolic Health
Insulin Resistance, Diabetes, and Red Light: An Evidence Firewall
ADA diagnostics, DPP effect sizes, and where photobiomodulation sits—experimental adjunct, not standard of care.
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Metabolic Health
HOMA-IR Explained: Formula, Cutoffs, and What It Is Not
(Fasting insulin × fasting glucose) / 405 in mg/dL units. Useful IR surrogate—not an ADA diabetes diagnostic criterion.
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Metabolic Health
Hemochromatosis Labs: Ferritin, TSAT, and the Testing Algorithm
AASLD-style path: TSAT ≥45% and/or high ferritin → HFE genotyping. Ferritin >1000 µg/L flags fibrosis risk; phlebotomy targets 50–100.
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