Topic
Evidence
Evidence is a recurring research topic on Health Canon. This hub collects related explainers and protocols, newest first, each with evidence grades and practical decision frameworks.
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Environmental Health
Parasite Overdiagnosis: When Not to Treat
In high-sanitation settings most bloating is not occult helminthiasis. No diagnosis → no chronic antiparasitic self-treatment. Endemic MDA ≠ Seattle herbal monthly deworming.
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Environmental Health
Global Burden of Soil-Transmitted Helminths and Neglected Tropical Diseases
STHs and other NTDs still cause massive disability in endemic regions; deworming and WASH are public health, not biohacking.
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Environmental Health
Parasite Prevention: Food, Water, Travel, and Household Hygiene
Prevention is exposure control—safe water, food hygiene, travel counseling, handwashing—not annual “parasite cleanses.”
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Environmental Health
Parasite Diagnostics: O&P Microscopy, Antigen Tests, and PCR
Stool O&P, antigen EIAs, and multiplex PCR have different sensitivity profiles—match method to clinical pretest probability.
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Nutrition
Organic Foods Sex Axes: Why Pregnancy and ART Change the Priority Stack
More produce still wins; organic’s highest-value window is exposure reduction in pregnancy and ART.
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Nutrition
Dirty Dozen and Clean Fifteen: Useful Budget Tool or Overstated Hazard List?
Residue rankings can triage organic spend—but they are not proof that conventional Dirty Dozen produce is illegal or toxic at residue doses.
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Hormones & Genes
MTHFR Is Not an Actionable Thrombophilia or CVD Indication
Unlike factor V Leiden, common MTHFR SNPs do not change anticoagulation or CVD prevention. Homocysteine-lowering RCTs failed hard outcomes; RPL management is not genotype-driven.
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Environmental Health
Mold and Damp Buildings Sex Axes: Pregnancy, Occupation, and Shared Remediation
Pregnancy and some occupational settings change mold risk communication; remediation hierarchy remains source control for everyone.
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Environmental Health
Microplastics Sex Axes: Semen, Placenta, and Shared Exposure Uncertainty
Microplastics appear in semen and placenta reports; dose metrics remain uncertain—sex-axis writing pairs findings with measurement humility.
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Metabolic Health
Insulin Resistance Sex Axes: Visceral Fat, PCOS, Menopause, and Shared Care
Men more often present visceral-fat IR patterns; women face PCOS and menopause transitions—shared SOC remains diet, weight, exercise, meds.
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Hormones & Genes
Fragrance and Endocrine Disruptors: Sex-Axis Synthesis for Men and Women
Women’s higher PCP exposure elevates some phthalate metabolites; male reproductive endpoints and female puberty/reproductive literature both matter.
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Men's Health
Fragrance, Phthalates, Male Testosterone and Sperm: Evidence Map
DEP/MEP from fragranced products join broader phthalate male reproductive literature—robust for some congeners, slight for others.
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Environmental Health
Fluoride Removal Technologies Compared: RO, Bone Char, Alumina, and Distillation
Activated carbon pitchers generally do not remove fluoride well; RO, distillation, and specialized media are the real options.
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Women's Health
Fluoride, Pregnancy, Sex Differences, and Neurodevelopment
NTP higher-exposure IQ findings, pregnancy biomarker studies, and occasional male-stronger signals sit beside CDC’s CWF safety position—dose and timing decide interpretation.
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Environmental Health
Fluoride Neurodevelopment and IQ: Mapping Contested Evidence Without Slogans
High natural fluoride and some epidemiologic IQ associations fuel debate; community fluoridation levels and confounding require careful grading.
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Environmental Health
Community Water Fluoridation Cost-Effectiveness: Caries Prevention Economics
At recommended levels, community fluoridation remains among the most cost-effective population dental interventions studied.
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Environmental Health
Fluoride Caries Prevention: Percent Reduction and Absolute Tooth Counts
CDC’s ~25% tooth-decay reduction framing, Community Guide absolute tooth counts, and NHMRC-linked ranges—with modern toothpaste context that shrinks incremental effects.
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Fitness
Fitness Sex Axes: Shared Training Laws for Adults (and What Still Differs)
Progressive overload, hard sets, protein, sleep, and energy availability are shared; pregnancy and AAS confounds are not.
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Environmental Health
EMF Sex Axes: Fertility, Pregnancy, and Shared Thermal Limits
Male fertility literature on RF/ELF is a research priority with heterogeneous findings; pregnancy content emphasizes standard device use and heat avoidance myths.
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Environmental Health
IARC EMF Classifications Deep Dive: ELF and RF Group 2B
ELF magnetic fields (2002) and radiofrequency fields (2011) are Group 2B—possibly carcinogenic. That is hazard identification, not a safety limit, and not Group 1 asbestos language.
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