Topic
Diagnostics
Diagnostics is a recurring research topic on Health Canon. This hub collects related explainers and protocols, newest first, each with evidence grades and practical decision frameworks.
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Environmental Health
Parasite Diagnostics Map: O&P, Antigen, PCR, and Serology
Match method to syndrome: microscopy O&P, stool antigen, multiplex PCR, and serology each answer different questions—with different false-negative windows.
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Environmental Health
ERMI, Air Culture, and Mold Testing Limits
ERMI is an EPA research-origin dust DNA index—not a validated medical diagnostic. CDC does not recommend routine home mold testing; moisture inspection first.
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Metabolic Health
TSAT and Iron Panel Algorithm for Hemochromatosis Screening
AASLD uses TSAT ≥45% as the sensitive phenotypic trigger (detects ~98–100% of C282Y homozygotes). Pair with ferritin, then HFE genotyping—do not use TSAT alone as phlebotomy endpoint.
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Environmental Health
Parasite Seroprevalence vs Active Infection: Why Antibodies Aren’t Always Disease
Serology can mean past exposure. Active infection needs syndrome, antigen/PCR/microscopy, or carefully timed serologic interpretation. Don’t treat titers as cleanses demand.
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Environmental Health
Urinary Mycotoxin Tests: Evidence Grade for Indoor Mold Claims
Commercial urine mycotoxin panels are poorly validated for diagnosing building-related illness. Diet, lab variability, and weak clinical utility undermine cleanse-driving results.
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Hormones & Genes
Allergy & Inflammation Testing: sIgE, SPT, OFC, FeNO, Eos & What Not to Order
History-first diagnostics for IgE disease versus T2 markers versus systemic CRP—stop using the wrong panel for the wrong question.
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Environmental Health
Parasite Diagnosis: O&P, Antigen, PCR, and Serology
Method must match the organism. One routine O&P does not rule out Crypto or pinworm.
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Metabolic Health
Diabetes Diagnostic Criteria: FPG, OGTT, and HbA1c Explained
ADA cut points define dysglycemia categories—not HOMA-IR and not one restaurant spike.
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Environmental Health
CIRS Evidence Grade vs Mainstream Mold Medicine
Damp buildings and respiratory risk are established. CIRS as a discrete diagnosis remains contested.
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