Evidence-dense health optimization

Subscribe
Health Canon
Browse

Topic

Thrombophilia

Thrombophilia is a recurring research topic on Health Canon. This hub collects related explainers and protocols, newest first, each with evidence grades and practical decision frameworks.

  1. Hormones & Genes

    MTHFR Is Not an Actionable Thrombophilia or CVD Indication

    Unlike factor V Leiden, common MTHFR SNPs do not change anticoagulation or CVD prevention. Homocysteine-lowering RCTs failed hard outcomes; RPL management is not genotype-driven.

    ELENA VOSS 4 MIN READ

  2. Hormones & Genes

    ACMG MTHFR Guideline: Do Not Routinely Genotype

    ACMG 2013 (with later addendum pathway) finds minimal clinical utility for common MTHFR SNPs—do not order for thrombophilia, RPL, or cascade relatives.

    ELENA VOSS 4 MIN READ

  3. Hormones & Genes

    ACMG MTHFR Testing Guidance: Why Routine SNP Orders Are Discouraged

    ACMG: do not order MTHFR polymorphism testing for thrombophilia or recurrent pregnancy loss. Fortification-era evidence dismantled the old causal chain.

    MARCUS CHEN 6 MIN READ

Frequently asked

About Thrombophilia

What is Thrombophilia?
Thrombophilia is a topic our editors cover across environmental health, metabolism, fitness, and recovery. This hub aggregates related guidance with citations.
How often is the Thrombophilia hub updated?
This hub updates when new articles are tagged Thrombophilia, so the latest coverage appears first.
Is Thrombophilia coverage medical advice?
No. Content is research synthesis for education. Personal medical decisions require a qualified clinician.