Topic
Immunology
Immunology is a recurring research topic on Health Canon. This hub collects related explainers and protocols, newest first, each with evidence grades and practical decision frameworks.
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Hormones & Genes
Non-IgE Hypersensitivity Pathways: FPIES, EoE, Contact & Cell-Mediated Allergy
Delayed food reactions, eosinophilic disease, and Type IV contact pathways—when IgE tests stay negative and the clock matters more than the panel.
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Hormones & Genes
Mast Cell & Basophil Effector Biology: Mediators, Triggers & Tryptase Kinetics
Tissue mast cells and circulating basophils release histamine, tryptase, lipids, and cytokines—IgE and non-IgE triggers, with tryptase as the practical activation clock.
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Hormones & Genes
Mast Cell Activation Syndrome: Consensus Criteria, Tryptase Rule & Overdiagnosis Risk
Vienna/AAAAI-aligned MCAS needs clinical episodes, laboratory mediator proof, and treatment response—not a symptom checklist.
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Metabolic Health
IgE Type I Hypersensitivity Explained
Sensitization, FcεRI, mast-cell degranulation—minutes that define classic allergy.
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